About mif
About mif
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MIF can generate its oncogenic signaling via equally autocrine and paracrine manners. MIF is understood to bind with the CD74 receptor to activate numerous inflammatory and survival pathways like MAPK and PI3K/Akt7, but the exact molecular system isn't absolutely understood. Curiously, CD74 or MIF blockade minimized the aggressiveness of invasive breast cancer cells8.
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Absorbance was measured at 590 nm. The absorbance correlates linearly to the quantity of residing cells in lifestyle, plus the IC50 benefit was calculated. Furthermore, cell viability was also assessed using a Prestoblue dye (Thermo).
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